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1

Identification of hydroxyhalobiphenyls as their methyl ethers by gas chromatography mass spectrometry

M. Th. M. Tulp, K. Olie, O. Hutzinger

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1977

Langue:

english

Fichier:

PDF, 604 KB

english, 1977

2

Identification of hydroxylated chlorodibenzo-p-dioxins, chlorodibenzofurans, chlorodiphenyl ethers and chloronaphthalenes as their methyl ethers by gas chromatography mass spectrometry

Martin Th. M. Tulp, Otto Hutzinger

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1978

Langue:

english

Fichier:

PDF, 604 KB

english, 1978

3

Fragmentation pathways in electron impact mass spectra of methoxyhalobiphenyls

Martin Th. M. Tulp, Stephen H. Safe, Robert K. Boyd

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1980

Langue:

english

Fichier:

PDF, 498 KB

english, 1980

4

ChemInform Abstract: New 1-Aryl-4-(biarylmethylene)piperazines as Potential Atypical Antipsychotics Sharing Dopamine D2-Receptor and Serotonin 5-HT1A-Receptor Affinities.

Rolf W. Feenstra, Janpeter de Moes, Jos J. Hofma, Henk Kling, Wilma Kuipers, Stephen K. Long, Martin Th. Tulp, Jan A. M. van der Heyden, Chris G. Kruse

Journal:

Année:

2001

Fichier:

PDF, 34 KB

2001

5

SLV310, a Novel, Potential Antipsychotic, Combining Potent Dopamine D2 Receptor Antagonism with Serotonin Reuptake Inhibition.

Rolf van Hes, Pieter Smid, Cees N. J. Stroomer, Koos Tipker, Martin Th. M. Tulp, Jan A. M. van der Heyden, Andrew C. McCreary, Mayke B. Hesselink, Chris G. Kruse

Journal:

Année:

2003

Fichier:

PDF, 6 KB

2003

6

Serotonergic receptors in anxiety and aggression; evidence from animal pharmacology

B. Olivier, M. Th. M. Tulp, J. Mos

Journal:

Human Psychopharmacology: Clinical and Experimental

Année:

1991

Langue:

english

Fichier:

PDF, 495 KB

english, 1991

7

Preclinical pharmacology of flesinoxan: A potential anxiolytic and antidepressant drug

J. Schipper, M. Th. M Tulp, B. Berkelmans, J. Mos, J. A. M. van der Heijden, B. Olivier

Journal:

Human Psychopharmacology: Clinical and Experimental

Année:

1991

Langue:

english

Fichier:

PDF, 2.25 MB

english, 1991

8

1,4-Benzodiazepines and 1,5-benzodiazocines XI. Synthesis and biological activity

Walter Heitmann, Hans Liepmann, Uwe Mätzel, Horst Zeugner, Andreas M Fuchs, Hermann Krähling, Michael Ruhland, Frans Mol, Martin Th.M Tulp

Journal:

European Journal of Medicinal Chemistry

Année:

1988

Langue:

english

Fichier:

PDF, 953 KB

english, 1988

9

Use of ethyl ethers, deuteriomethyl ethers and cyclic n-butylboronates of hydroxychlorobiphenyls in identification of metabolites of polychlorinated biphenyls

Martin Th.M. Tulp, Otto Hutzinger

Journal:

Journal of Chromatography A

Année:

1977

Langue:

english

Fichier:

PDF, 573 KB

english, 1977

10

New 1-aryl-4-(biarylmethylene)piperazines as potential atypical antipsychotics sharing dopamine D2-receptor and serotonin 5-HT1A-receptor affinities

Rolf W Feenstra, Janpeter de Moes, Jos J Hofma, Henk Kling, Wilma Kuipers, Stephen K Long, Martin Th.M Tulp, Jan A.M van der Heyden, Chris G Kruse

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 151 KB

english, 2001

11

SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition

Rolf van Hes, Pieter Smid, Cees N.J Stroomer, Koos Tipker, Martin Th.M Tulp, Jan A.M van der Heyden, Andrew C McCreary, Mayke B Hesselink, Chris G Kruse

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2003

Langue:

english

Fichier:

PDF, 144 KB

english, 2003

12

Synthesis and structure–Activity data of some new epibatidine analogues

Jean-Paul G. Seerden, Martin Th.M. Tulp, Hans W. Scheeren, Chris G. Kruse

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 178 KB

english, 1998

13

C5-Substituted Derivatives of 5-OMe-BPAT: Synthesis and Interactions with Dopamine D2 and Serotonin 5-HT1A Receptors

Evert J. Homan, Martin Th.M. Tulp, Jonas E. Nilsson, Håkan V. Wikström, Cor J. Grol

Journal:

Bioorganic & Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 182 KB

english, 1999

14

Serotonin agonists and antagonists. Pharmacological tools and therapeutics

I. van Wijngaarden, M. Th. M. Tulp, W. Soudijn

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Année:

1993

Langue:

english

Fichier:

PDF, 458 KB

english, 1993

15

Synthesis and receptor-affinity profile of N-hydroxytryptamine derivatives for serotonin and tryptamine receptors. A molecular-modeling study

Gerard D. H. Dijkstra, Martin Th. M. Tulp, Pedro H. H. Hermkens, Jan H. van Maarseveen, Hans W. Scheeren, Chris G. Kruse

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Année:

1993

Langue:

english

Fichier:

PDF, 769 KB

english, 1993

16

Relationship between electrocortical activity and Β-adrenergic receptor function in the rat after chronic desimipramine treatment

F. N. C. Krijzer, J. Schipper, M. Th. M. Tulp, P. A. R. Koopman

Journal:

Journal of Neural Transmission

Année:

1989

Langue:

english

Fichier:

PDF, 1008 KB

english, 1989

17

Abstracts of papers

J. F. Rodrigues de Miranda, J. van der Weide, P. C. Tepper, J. B. de Vries, A. S. Horn, A. P. Ijzerman, T. Bultsma, H. Timmerman, M. Th. M. Tulp, L. H. M. Janssen, D. de Kaste, K. J. H. van Buuren, W.

Journal:

International Journal of Clinical Pharmacy

Année:

1985

Langue:

english

Fichier:

PDF, 768 KB

english, 1985

18

Abstracts of papers medicinal chemistry meeting

H. Timmerman, J. Wilting, M. Th. M. Tulp, J. Kelder, Pramod R. Saxena, J. M. Nueten, W. J. Janssens, A. Bast, E. J. Freyne, A. H. M. Raeymaekers, J. Gelder, M. G. Venet, V. K. Sipido, F. Clerck, Guy L

Journal:

International Journal of Clinical Pharmacy

Année:

1988

Langue:

english

Fichier:

PDF, 888 KB

english, 1988

19

N4-Unsubstituted N1-Arylpiperazines as High-Affinity 5-HT1A Receptor Ligands

Kuipers, Wilma, van Wijngaarden, Ineke, Kruse, Chris G., van Amstel, Marian ter Horst, Tulp, Martin Th. M., IJzerman, Adriaan P.

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 3.25 MB

english, 1995

20

ChemInform Abstract: A Series of N4-Imidoethyl Derivatives of 1-(2,3-Dihydro-1,4- benzodioxin-5-yl)piperazine as 5-HT1A Receptor Ligands: Synthesis and Structure-Affinity Relationships.

B. J. VAN STEEN, I. VAN WIJNGAARDEN, M. TH. M. TULP, W. SOUDIJN

Journal:

Année:

1996

Fichier:

PDF, 32 KB

1996

21

Reductive dechlorination of chlorobiphenylols by rats

M. Th. M. Tulp, W. A. Bruggeman, O. Hutzinger

Journal:

Cellular and Molecular Life Sciences

Année:

1977

Langue:

english

Fichier:

PDF, 271 KB

english, 1977

22

Idaverine, an M2- vs. M3-selective muscarinic antagonist, does not prevent motion sickness in cats

James B. Lucot, Karin J. van Charldorp, Martin Th.M. Tulp

Journal:

Pharmacology Biochemistry and Behavior

Année:

1991

Langue:

english

Fichier:

PDF, 532 KB

english, 1991

23

The concept of selectivity in 5-HT receptor research

I. Van Wijngaarden, M.Th.M. Tulp, W. Soudijn

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 900 KB

english, 1990

24

Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed

Rob Leurs, Martin Th.M. Tulp, Wiro M.B.P. Menge, Martin J.P. Adolfs, Obbe P. Zuiderveld, Hendrik Timmerman

Journal:

British Journal of Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1995

25

Differential effects of metoclopramide and zetidoline on gastrointestinal motility

Marinus W. Lobbezzo, Felix H.A. Janszen, Martin Th.M. Tulp, Jan M.A. Zwagemakers

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 546 KB

english, 1985

26

Flesinoxan lowers blood pressure and heart rate in cats via 5-HT1A receptors

Wout Wouters, Martin Th.M. Tulp, Paul Bevan

Journal:

European Journal of Pharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 789 KB

english, 1988

27

Remarkable effects of 5-HT3-antagonists on spontaneous and induced etectrocortical activity in the rat

F.N.C. Krijzer, M.Th.M. Tulp

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 102 KB

english, 1990

28

5-HT-receptors in porcine basilar arteries closely resemble 5-HT1D-binding sites

K.J. van Charldorp, M.Th.M. Tulp, B. Hendriksen, H. Mons, P. Couwenberg, W. Wouters

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 222 KB

english, 1990

29

Receptor binding profiles of potent and ‘selective’ 5-HT1A receptor ligands

M.Th.M. Tulp, F. Mol

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 103 KB

english, 1990

30

Ethopharmacological studies differentiate the effects of various serotonergic compounds on aggression in rats

J. Mos, B. Olivier, Th.M. Tulp

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 94 KB

english, 1990

31

Serenics: pharmacology and metabolism

B. Olivier, J. Mos, M. Raghoebar, H.J. Koster, M.Th.M. Tulp

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 115 KB

english, 1990

32

Molecular pharmacology of 5-HT-uptake inhibitors: inhibition of monoamine uptake, receptor binding profile and functional receptor antagonism

F. Mol, M.Th.M. Tulp, J. Schipper, K.J. van Charldorp

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 89 KB

english, 1990

33

Adrenoceptors and dopamine receptors are not involved in the discriminative stimulus effect of the 5-HT1A receptor agonist flesinoxan

Caroline E. Ybema, Berend Olivier, Jan Mos, Martin Th.M. Tulp, Jef L. Slangen

Journal:

European Journal of Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 589 KB

english, 1994

34

The metabolism of 4,4′-dichlorobiphenyl in rats and frogs

M.Th.M. Tulp, G. Sundström, O. Hutzinger

Journal:

Année:

1976

Langue:

english

Fichier:

PDF, 336 KB

english, 1976

35

The interaction of 1-(2-(diarylmethoxy)ethyl)aziridines with histamine receptors in the longitudinal muscle strip of the guinea pig ileum

Martin Th.M. Tulp, Johan Zaagsma

Journal:

European Journal of Pharmacology

Année:

1977

Langue:

english

Fichier:

PDF, 354 KB

english, 1977

36

Environmental chemistry of PCB-replacement compounds - V - the metabolism of chloro-isopropylbiphenyls in fish, frogs, fungi and bacteria

M.Th.M. Tulp, G.M. Tillmanns, O. Hutzinger

Journal:

Année:

1977

Langue:

english

Fichier:

PDF, 323 KB

english, 1977

37

Environmental chemistry of PCB-replacement compounds - III - the metabolism of 4-chloro-4′-isopropylbiphenyl and 2,5-dichloro-4′-isopropylbiphenyl in the rat

M.Th.M. Tulp, G. Sundström, J.C. de Graaff, O. Hutzinger

Journal:

Année:

1977

Langue:

english

Fichier:

PDF, 286 KB

english, 1977

38

Rat metabolism of polychlorinated dibenzo-p-dioxins

M.Th.M. Tulp, O. Hutzinger

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 322 KB

english, 1978

39

The bacterial metabolism of 4,4′-dichlorobiphenyl, and its suppression by alternative carbon sources

M.Th.M. Tulp, R. Schmitz, O. Hutzinger

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 270 KB

english, 1978

40

Some thoughts on aqueous solubilities and partition coefficients of PCB, and the mathematical correlation between bioaccumulation and physico-chemical properties

M.Th.M. Tulp, O. Hutzinger

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 753 KB

english, 1978

41

Environmental chemistry of PCB-replacement compounds - VI - composition and metabolism of Wemcol ®, an isopropylbiphenyl formulation

M.Th.M. Tulp, G.C. van Stein, O. Hutzinger

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 542 KB

english, 1978

42

Effect of salinity on uptake of 14C-2,2′4,5,5′-pentachlorobiphenyl by juvenile Atlantic salmon

M.Th.M. Tulp, K. Haya, W.G. Carson, V. Zitko, O. Hutzinger

Journal:

Année:

1979

Langue:

english

Fichier:

PDF, 420 KB

english, 1979

43

Structure-Affinity Relationship Studies on 5-HT1A receptor Ligands. 2. Heterobicyclic Phenylpiperazines with N4-Aralkyl Substituents

van Steen, Bart J., van Wijngaarden, Ineke, Tulp, Martin Th. M., Soudijn, Willem

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 3.79 MB

english, 1994

44

5-HT 1A - versus D 2 -Receptor Selectivity of Flesinoxan and Analogous N 4 -Substituted N 1 -Arylpiperazines

Kuipers, Wilma, Kruse, Chris G., van Wijngaarden, Ineke, Standaar, Piet J., Tulp, Martin Th. M., Veldman, Nora, Spek, Anthony L., IJzerman, Adriaan P.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 470 KB

english, 1997

45

A Series of N4-Imidoethyl Derivatives of 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine as 5-HT1A Receptor Ligands: Synthesis and Structure-Affinity Relationships

van Steen, B. J., van Wijngaarden, I., Tulp, M. Th. M., Soudijn, W.

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 735 KB

english, 1995

46

Metabolism of Chlorodiphenyl Ethers and Irgasan® DP 300

Tulp, M. Th. M., Sundström, G., Martron, L. B. J. M., Hutzinger, O.

Journal:

Année:

1979

Langue:

english

Fichier:

PDF, 861 KB

english, 1979

47

NEUROCHEMICAL PROFILE OF ELTOPRAZINE

Schipper, J., Tulp, M.Th.M., Sijbesma, H.

Journal:

Drug Metabolism and Drug Interactions

Année:

1990

Langue:

english

Fichier:

PDF, 2.96 MB

english, 1990

48

Receptor Binding Profiles of Amiloride Analogues Provide no Evidence for a Link Between Receptors and the Na + /H + Exchange, But Indicate a Common Structure on Receptor Proteins

Garritsen, Anja, Ijzerman, Adriaan P., Th. Tulp, Martin M., Cragoe, Edward J., Soudijn, Willem

Journal:

Journal of Receptor and Signal Transduction Research

Année:

1991

Langue:

english

Fichier:

PDF, 890 KB

english, 1991

49

ChemInform Abstract: 2-Phenylpyrroles as Conformationally Restricted Benzamide Analogues. A New Class of Potential Antipsychotics. Part 1.

VAN WIJNGAARDEN, I., KRUSE, C. G., VAN HES, R., VAN DER HEYDEN, J. A. M., TULP, M. TH. M.

Journal:

Année:

1988

Fichier:

PDF, 156 KB

1988

50

[Pharmacochemistry Library] Serotonin Receptors And Their Ligands Volume 27 || Ligand binding assays

Année:

1997

Langue:

english

Fichier:

PDF, 250 KB

english, 1997